Search Results for: subcutaneous t-cell lymphoma

Histologic Diagnosis of Inflammatory Skin Diseases

Adult T-cell leukemia/lymphoma

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Key Points

…l papillae, and evidence of gluten-sensitive enteropathy. Symmetric involvement of bilateral extensor surfaces, scalp, and buttocks, with purpuric lesions on the fingers and toes is the classic presentation. DH is mediated by IgA autoantibodies,…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Treatment

…vement is inadequate. Check the CBC every 2 weeks as the dose is increased. Alternative steps Gluten-free diet: Because dermatitis herpetiformis is gluten dependent, most patients will respond to a gluten-free diet. However, the response to gluten…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Key Points

…yte necrosis on histology has been shown to have worse prognosis. Additionally, severe GI and respiratory involvement (the latter in the form of bronchiolitis obliterans) may be seen, which may be a source of considerable morbidity and mortality….

Differential Diagnosis in Dermatopathology

Lymphocytoma cutis with lymphoid follicles vs. Follicular-cell lymphoma

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

Therapeutic Strategies in Dermatology

Lichen Planus: Initial Evaluation

…lopecia), or with lichenoid rash, scaly scalp patches, and noncicatricial loss of axillary and pubic hair (Lassueur-Graham-Little-Piccardi syndrome). Other variants include actinic lichen planus (photodistributed), lichen planus pigmentosum,…

Therapeutic Strategies in Dermatology

Hand Dermatitis: Key Points

Key Points Hand dermatitis may be difficult to treat due to the thickened skin surface of the hands and the frequent exposure of the hands to irritants and potentially exacerbating factors. Hand dermatitis can range from an acute, extremely…

Therapeutic Strategies in Dermatology

Persistent Pigmented Purpuric Dermatitis: Overview

…d pigmented purpura (of Gougerot and Blum), eczematoid purpura of Doucas and Kapetanakis (disseminated pruriginous angiodermatitis), and lichen aureus. For the most part, these conditions are idiopathic, although a pigmented purpuric drug eruption…