Search Results for: vesicle

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Method for Surgery

…thologist with sections from which an element critical for diagnosis, i.e., the epidermis, is missing (Fig. 4.1). Tiny tense vesicles, such as those of miliaria crystallina, dyshidrotic dermatitis, and infection by herpesvirus, are an exception to…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ls in the dermis and in vesicles in the epidermis = Bullous pemphigoid, vesicular Both authentic intraepidermal (spongiotic) vesicles and subepidermal vesicles are present. In addition, some intraepidermal vesicles have ruptured to become…

Histologic Diagnosis of Inflammatory Skin Diseases

Fixation of the Specimen

…rilesional” zone should be noneroded, noncrusted, and nonvesicular. With rare exceptions, a biopsy specimen of a frank vesicle is useless for interpretation by direct immunofluorescence. In contrast, a biopsy performed for direct…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…but one of many expressions of leukocytoclastic vasculitis clinical (others being purpuric macules, purpuric and nonpurpuric vesicles, and ulcers), and, moreover, diseases unrelated to leukocytoclastic vasculitis (lichenoid purpura of Gougerot and…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…s, intraepidermal, spongiotic + 10.88.6B: Collections of neutrophils beneath the cornified layer at the side of a spongiotic vesicle. + 10.88.6C + 10.88.6D: = Prurigo pigmentosa Vesicles in prurigo pigmentosa may come into being by virtue of…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…pesvirus infection, fully developed If this lesion had not been interrupted by biopsy, the tension within the intraepidermal vesicle would have caused it to burst and to become subepidermal, too; only a single layer of basal keratocytes remains at…