Search Results for: vesicle

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Method for Surgery

…thologist with sections from which an element critical for diagnosis, i.e., the epidermis, is missing (Fig. 4.1). Tiny tense vesicles, such as those of miliaria crystallina, dyshidrotic dermatitis, and infection by herpesvirus, are an exception to…

Differential Diagnosis in Dermatopathology

Urticarial reaction to an arthropod assault vs. Urtica

Circular orange-red-blue macule(s) or patch(es) that often becomes a papule(s) or plaque(s) and vesiculates, healing with hyperpigmentation, and that occurs repeatedly at the very same cutaneous and/or mucous membrane site(s), especially the…

Histologic Diagnosis of Inflammatory Skin Diseases

Urticaria

…ate of lymphocytes and eosinophils in conjunction with edema of the papillary dermis and spongiosis (sometimes, a spongiotic vesicle) in the epidermis at the site of the “bite.” Laboratory confirmation None exists. Cause and mechanism…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermoepithelial Interface

…ils; BC, basal cell; D, dermis; HD, hemidesmosome; LD, lamina densa; LL, lamina lucida; PM, plasma membrane; PV, pinocytotic vesicle. (x67,500) (Courtesy of Stephen Katz, M.D.) The plasma membrane of basal keratocytes forms the roof of the…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…but one of many expressions of leukocytoclastic vasculitis clinical (others being purpuric macules, purpuric and nonpurpuric vesicles, and ulcers), and, moreover, diseases unrelated to leukocytoclastic vasculitis (lichenoid purpura of Gougerot and…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…necrosis of the epidermis follows on severe ballooning and reticular alteration that are accompaniments of an intraepidermal vesicle. 10.99.3A: Vasculitis, small vessel, neutrophilic + 10.99.3B: Perivascular and interstitial mixed-cell infiltrate…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…s, intraepidermal, spongiotic + 10.88.6B: Collections of neutrophils beneath the cornified layer at the side of a spongiotic vesicle. + 10.88.6C + 10.88.6D: = Prurigo pigmentosa Vesicles in prurigo pigmentosa may come into being by virtue of…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…tiforme The subepidermal blister came into being as a result of rupture of tense intraepidermal vesicles. The intraepidermal vesicles developed mostly as a consequence of ballooning of keratocytes, rather than of spongiosis. 10.32.4A: Vesicular…