Search Results for: x-linked ichthyosis

Histologic Diagnosis of Inflammatory Skin Diseases

Nerves

…corpuscles, however, mucocutaneous end organs cannot be visualized in sections prepared conventionally and stained by hematoxylin and eosin. The structures, on exposure to silver stains, are seen to consist of loops of loosely wound, branching…

Histologic Diagnosis of Inflammatory Skin Diseases

Ground Substance

Ground substance (extrafibrillar matrix) is finely granular extracellular material that enmeshes fibrillar and cellular components of the body, including those of the dermis, binds water, and provides hydration to the skin. The ground substance of…

Histologic Diagnosis of Inflammatory Skin Diseases

Elastic Fibers

…le measure for the lax, bulging skin characteristic of that condition. Hereditary defects of elastic fibers, such as cutis laxa and pseudoxanthoma elasticum, display loose skin that does not return, in normal fashion, to its original shape after…

Histologic Diagnosis of Inflammatory Skin Diseases

Eccrine Units

…rk cells that have dense granules. The luminal border displays numerous villi. Myoepithelial cells surround secretory ones. (x7000) (Courtesy of Ken Hashimoto, M.D.) Eccrine glands on the palms, soles, axillae, and forehead, unlike those on the rest…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Acquired Epidermolysis Bullosa?

…oring fibrils in addition to the lamina densa and possibly anchoring plaques, and thus has the same distribution as the carboxy terminus of type VII collagen.” The antigen of acquired epidermolysis bullosa subsequently was found to be the…

Patients affected by endemic pemphigus foliaceus in Colombia, South America exhibit autoantibodies to optic nerve sheath envelope cell junctions

Patients affected by endemic pemphigus foliaceus in Colombia, South America exhibit autoantibodies to optic nerve sheath envelope cell junctions

…ptoms including blurred, hazy, or “milky” vision, refractory defects and amblyopia (P < 0.001). In addition, external examination of the El Bagre-EPF patients displayed entropion and/or ectropion, trichiasis, blepharophimosis, thinned...