Search Results for: psoriasis

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Histologic Diagnosis of Inflammatory Skin Diseases

Limitations of the Algorithmic Method

…hod by pattern analysis in reference to a configuration of epidermis that resembles the shape of a fully developed lesion of psoriasis, conceptually all epidermal manifestations of psoriasis are psoriasiform equally, including very…

Differential Diagnosis in Dermatopathology

Discussions

…oma is abundant, in contrast to psoriasis in which it is little. This differential diagnosis between pale-cell acanthoma and psoriasis is applicable only to plaques of psoriasis in which there are elongated rete ridges of uniform length and pallor…

Differential Diagnosis in Dermatopathology

Discussions

…221;), and that of pityriasis rubra pilaris is of normal thickness or greater. Edema is prominent in the papillary dermis of psoriasis, but not in that of pityriasis rubra pilaris. Psoriasis affects approximately 2% of the population of the United…

Differential Diagnosis in Dermatopathology

Discussions

…apular, and axillary regions. Seborrheic dermatitis is a common condition, affecting about 20% of all adults, in contrast to psoriasis which affects about 2% of them. Occasionally, psoriasis has predilection for seborrheic areas. In that…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ified layer with its basket-weave configuration. Dilated tortuous capillaries in dermal papillae are reminiscent of those in psoriasis, but this lesion is not psoriasis because there are no thin rete ridges of equal length, no thin suprapapillary…

Histologic Diagnosis of Inflammatory Skin Diseases

Pityriasis rubra pilaris

…te in both vertical and horizontal directions in company with a granular zone that is largely intact. In evolving lesions of psoriasis, by contrast, parakeratosis takes the form of mounds that often have neutrophils at their summit, and the granular…

Differential Diagnosis in Dermatopathology

Discussions

…y, as would be expected for conditions whose lesions last for weeks or months (and even years in the case of some lesions of psoriasis). Clinically, psoriasis begins as tiny, red macules that soon enlarge to become slightly elevated and scaly. Early…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…phocytes = Lichen striatus + Mitotic figures above the basal layer and a dilated tortuous capillary in each dermal papilla = Psoriasis, guttate + Mounds of parakeratosis, individual necrotic keratocytes, lymphocytes along the dermoepidermal…

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