Search Results for: squamous-cell carcinoma

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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cutaneous T-cell Lymphoma?

…etimes involves the skin as does adult T-cell lymphoma/leukemia. Uncommonly, Hodgkin’s disease is an expression of a T-cell, rather than of a B-cell, lymphoma, and rarely it may appear in the skin. In that circumstance, it also qualifies as a…

Sebaceous carcinoma in situ as a concept and diagnostic entity

Sebaceous carcinoma in situ as a concept and diagnostic entity

…, namely, benign lesion, carcinoma in situ and invasive carcinoma. When the term carcinoma used unmodified, such as squamous cell carcinoma, sebaceous carcinoma, adenocarcinoma, generally means invasive carcinoma. Non-invasive carcinoma is…

Adult T-cell leukemia/lymphoma: a case report of primary cutaneous tumoral type

Adult T-cell leukemia/lymphoma: a case report of primary cutaneous tumoral type

…ed by NF-κβ, AP-1 and SRF for example. Tax protein also interferes with function of p53, p16 and MAD1, preventing infected T-cells to undergo cell cycle arrest by DNA damage checkpoints or induction of apoptosis, thus inducing genetic instability….

Histologic Diagnosis of Inflammatory Skin Diseases

Adult T-cell leukemia/Lymphoma

…fungoides. Laboratory confirmation Atypical multilobulated lymphocytes can be found in the peripheral blood. The neoplastic cells exhibit clonal rearrangement of the T-cell receptor gene and express CD2, CD3, CD4, and CD25. Cause and mechanism The…

Langerhans cell histiocytosis-a case report

Langerhans cell histiocytosis-a case report

…ph node or visceral enlargements. One scalp lesion and another one from the perineum were biopsied and both revealed a dense cellular infiltrate made up of mononuclear cells with conspicuous eosinophilic cytoplasm and large cleaved vesicular…

Extraocular sebaceous carcinoma: a series of three cases with varied presentation

Extraocular sebaceous carcinoma: a series of three cases with varied presentation

…cularly common in eyelid tumours. An exclusively in-situ component may rarely occur and differentiating this from an in-situ squamous carcinoma may be extremely difficult, especially if sebocytic differentiation is sparse. A thorough histologic…

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