Search Results for: ballooning

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…arakeratosis in resolving lesions 2. Psoriasiform acanthosis in time 2. No psoriasiform acanthosis 3. Spongiosis, but little ballooning, in the epidermis 3. Ballooning, but little spongiosis, in the epidermis 4. Very few, if any, individual necrotic…

Histologic Diagnosis of Inflammatory Skin Diseases

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…ar stage The vesicle in incontinentia pigmenti comes into being as a rule solely by spongiosis. This example is exceptional; ballooning is present as well as spongiosis. 10.50.5A: Perivascular dermatitis, psoriasiform + 10.50.5B: Many dyskeratotic…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

…lteration, a smudged appearance of that junction, a thickened basement membrane), in the viable epidermis (e.g., spongiosis, ballooning, acantholysis), and/or in the cornified layer (e.g., parakeratosis in mounds that house neutrophils,…

Histologic Diagnosis of Inflammatory Skin Diseases

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…stinguished from those of graft-versus-host disease. The paucity of the infiltrate of lymphocytes and confinement of necrotic keratocytes to the lower part of the epidermis in the absence of either spongiosis or ballooning militate against erythema…

Balloon cell melanoma in primary care practice: a case report

Balloon cell melanoma in primary care practice: a case report

…f balloon cells has been confirmed both by immunohistochemical studies [12] and electron microscopy, which revealed that the ballooning change was due to progressive vacuolisation of melanosomes [13,14,15]. BCMM is characterised by aggregations of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mucha-Habermann Disease a Lymphocytic Vasculitis?

…alteration there, and they are present, too, in an epidermis punctuated by individual necrotic keratocytes, spongiosis, and ballooning. In lesions evolving, mounds of parakeratosis house neutrophils. Erythrocytes are extravasated in the papillary…

Histologic Diagnosis of Inflammatory Skin Diseases

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…necrotic keratocytes = Herpesvirus infection, near fully developed The sequence of events in the epidermis was extraordinary ballooning of keratocytes that led to intraepidermal vesiculation accompanied by reticular alteration of the spinous zone…