Search Results for: melanocytes

Non-choroidal yellow melanoma showing positive staining with Sudan Black consistent with the presence of lipofuscin: a case report

Non-choroidal yellow melanoma showing positive staining with Sudan Black consistent with the presence of lipofuscin: a case report

…s a nodular, well circumscribed proliferation of melanocytes (Figure 3). There was a proliferation of cytologically abnormal melanocytes and some confluent nests of melanocytes at the dermoepidermal junction (Figure 5), and the junctional…

In vivo reflectance confocal microscopy features of a melanoacanthoma

In vivo reflectance confocal microscopy features of a melanoacanthoma

…yperkeratosis, acanthosis and horn pseudocysts, as well as islands of small basaloid cells intermingled with large dendritic melanocytes. The melanocytes are large, dendritic, contain abundant melanin, and are not restricted to the basal cell layer…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

-oid?

…nevus is one of many synonyms for Spitz nevus. To date, there has yet to be a comprehensible description of the epithelioid melanocytes said to constitute that distinctive nevus. Because, in times past, the phrase “spindle and/or epithelioid…

Regression of nevi in a melanoma patient treated with interferon

Regression of nevi in a melanoma patient treated with interferon

…lanoma-associated leukoderma. These phenomena result from an immune reaction against shared antigens on benign and malignant melanocytes [5,6]. Hu and colleagues described primary melanomas presenting as inflamed pigmented lesions during adjuvant…

Histologic Diagnosis of Inflammatory Skin Diseases

Langerhans’ Cells

…eratocytes by a space, a finding that for more than a century caused them to be interpreted incorrectly as “high-level melanocytes.” In fact, the space that surrounds Langerhans” cells is an artifact caused by shrinkage during…

An irregular pigmented lesion on the back

An irregular pigmented lesion on the back

…ust a coincidental collision between tumors [2]. These mutations may result in an altered cell-to-cell communication between melanocytes and keratinocytes that would lead to an abnormal proliferation of melanocytes and/or keratinocytes [2]. Taking…

In vivo intraoral reflectance confocal microscopy of an amalgam tattoo

In vivo intraoral reflectance confocal microscopy of an amalgam tattoo

…ls suggesting a reactive lymphohistiocytic infiltrate. To better characterize these findings, immunohistochemical stains for melanocytes and Langerhans cells were performed. These showed normal numbers of melanocytes within the basal and…

Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update

Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update

…howed a widespread derma atrophy (B) with large sheets of epithelioid cells at the junction (C); cytomorphologically, dermal melanocytes were epithelioid but devoid of true ‘Spitzoid’ features (D). The excision specimen showed a bland junctional…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Changing Mole?

…nge independently should be cause for alarm.” Rhodes AR. Neoplasms: benign neoplasias, hyperplasias, and dysplasias of melanocytes. In: Fitzpatrick TB, Eisen AZ, Wolff K, et al., eds., Dermatology in general medicine. 4th ed. New York:…