Search Results for: melanocytes

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

-oid?

…nevus is one of many synonyms for Spitz nevus. To date, there has yet to be a comprehensible description of the epithelioid melanocytes said to constitute that distinctive nevus. Because, in times past, the phrase “spindle and/or epithelioid…

Non-choroidal yellow melanoma showing positive staining with Sudan Black consistent with the presence of lipofuscin: a case report

Non-choroidal yellow melanoma showing positive staining with Sudan Black consistent with the presence of lipofuscin: a case report

…s a nodular, well circumscribed proliferation of melanocytes (Figure 3). There was a proliferation of cytologically abnormal melanocytes and some confluent nests of melanocytes at the dermoepidermal junction (Figure 5), and the junctional…

Regression of nevi in a melanoma patient treated with interferon

Regression of nevi in a melanoma patient treated with interferon

…lanoma-associated leukoderma. These phenomena result from an immune reaction against shared antigens on benign and malignant melanocytes [5,6]. Hu and colleagues described primary melanomas presenting as inflamed pigmented lesions during adjuvant…

In vivo reflectance confocal microscopy features of a melanoacanthoma

In vivo reflectance confocal microscopy features of a melanoacanthoma

…yperkeratosis, acanthosis and horn pseudocysts, as well as islands of small basaloid cells intermingled with large dendritic melanocytes. The melanocytes are large, dendritic, contain abundant melanin, and are not restricted to the basal cell layer…

An irregular pigmented lesion on the back

An irregular pigmented lesion on the back

…ust a coincidental collision between tumors [2]. These mutations may result in an altered cell-to-cell communication between melanocytes and keratinocytes that would lead to an abnormal proliferation of melanocytes and/or keratinocytes [2]. Taking…

Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update

Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update

…howed a widespread derma atrophy (B) with large sheets of epithelioid cells at the junction (C); cytomorphologically, dermal melanocytes were epithelioid but devoid of true ‘Spitzoid’ features (D). The excision specimen showed a bland junctional…

Atypical dermoscopic presentation of an acral congenital melanocytic nevus in an adult: parallel ridge pattern and its histologic correlation

Atypical dermoscopic presentation of an acral congenital melanocytic nevus in an adult: parallel ridge pattern and its histologic correlation

…r-cut congenital-like features. (B) (40x H&E stain) An intradermal combination of type C and dendritic (blue nevus-like) melanocytes. (C) (40x H&E stain) Striking acrosyringial and periductal distribution. (D) (20x H&E stain) Mainly…

When all you have is a dermatoscope—start looking at the nails

When all you have is a dermatoscope—start looking at the nails

…continuous, longitudinal pigmented streaks (longitudinal melanonychia) may either be caused by a benign activation of matrix melanocytes (e.g., as a result of trauma, inflammation, or adverse drug reactions) or by a true melanocytic proliferation…