Search Results for: erythema multiforme

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Histologic Diagnosis of Inflammatory Skin Diseases

Images

…cells on lobules, tuberculoid granulomas at the periphery of lobules, and fibrosis in the center of markedly widened septa = Erythema nodosum Erythema nodosum begins in septa with predominance of neutrophils, progresses to preponderance of…

Differential Diagnosis in Dermatopathology

Discussions

…tiating outlined at the outset enable a histopathologist to render a diagnosis with precision. The early lesions clinical of erythema multiforme are edematous papules that soon become slightly purpuric plaques on which blisters form. When a papule…

Differential Diagnosis in Dermatopathology

Discussions

…ted diseases, one of which had been characterized clinically about 100 years before by Hebra and named by that dermatologist erythema multiforme exudativum, and the other approximately 75 years previously by Ritter, a German dermatologist, and…

Differential Diagnosis in Dermatopathology

Discussions

…n along the dermoepidermal junction. Intra- and subepidermal vesicles concurrent is an attribute sometimes of both diseases. Erythema multiforme differs from fixed drug eruption by having a dermal infiltrate that is sparse, superficial, mostly…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Paraneoplastic Pemphigus?

…scribed as confluent erythema on the trunk and papules that sometimes eventuated in target-like vesicles resembling those of erythema multiforme on the trunk and extremities. The mucosal lesions were painful erosions. In brief, the features clinical…

Differential Diagnosis in Dermatopathology

Discussions

…involvement of mucous membranes, and signs of systemic illness, such as high fever and hypotension. Toxic shock syndrome and erythema multiforme also have findings histopathologic in common, among them superficial perivascular infiltration by…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…and vacuolar alteration along the dermoepidermal interface, and a perivascular and interstitial infiltrate of lymphocytes = Erythema multiforme + Individual necrotic keratocytes, lymphocytes, neutrophils, and eosinophils in conjunction with…

Differential Diagnosis in Dermatopathology

Discussions

…, save for a few eosinophils episodically. Despite these many changes histopathologic in common, a fully-developed lesion of erythema multiforme usually can be differentiated from acute graft-versus-host disease by its normal cornified layer, the…

Histologic Diagnosis of Inflammatory Skin Diseases

Drug eruptions

…be found in a host of inflammatory processes that in most circumstances are unaccompanied with them, e.g., pityriasis rosea, erythema multiforme, psoriasis, and lichen planus. In short, the mere presence of eosinophils does not, in itself, denote a…

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