- Atopic dermatitis is a chronic, intermittent disease. It is most prevalent in children but affects all ages.
- Atopic dermatitis is commonly found in association with allergic rhinitis, asthma, or other manifestations of atopy.
- There are three likely related pathophysiologic mechanisms underlying the disease: skin inflammation (T helper cell dysregulation), an epidermal barrier defect (ceramide, filaggrin) and genetics.
- Treatment involves an initial therapy to reduce inflammation as well as a long-term maintenance regimen. Skin care is critical to the initial treatment and to the maintenance plan.