Clinical Reference / Therapeutic Strategies / Basal Cell Carcinoma

Basal Cell Carcinoma

Key Points

  • Basal cell carcinoma is (BCC) an extremely common skin cancer that typically presents late in life as a slow growing pearly papule with central ulceration on sun exposed areas. Other subtypes of BCC differ in their presentation.
  • Accurate and timely diagnosis is essential to guide the appropriate management of BCC, and a skin biopsy is recommended for diagnosis and to help guide treatment. When let untreated BCC are locally destructive but rarely metastasize.
  • Surgical excision is almost always the first-line treatment for BCC. Mohs micrographic surgery is a tissue-sparing surgical excision technique that may be used to remove lesions on the face or other body sites where wide excision is not feasible
  • Basal cell nevus syndrome (Gorlin syndrome) is a rare autosomal dominant genetic disorder characterized by frequent BCC, and should be suspected in any child presenting with BCC. Treatment with radiation is contraindicated in this population.
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